Dr. Christine Vande Velde is an Assistant Professor at CHUM-Université de Montréal. She is an expert on understanding the mechanisms underlying ALS. In particular, she has focused her work both on the energy producing structures in cells called mitochondria, and their involvement in the disease, as well as understanding the function of structures called stress granules in ALS. Dr. Vande Velde is the lead investigator on a 2015 ALS Canada-Brain Canada Arthur J. Hudson Translational Team Grant.
Credit: Amy Dumbleton
Dr. Alex Parker is an Assistant Professor at CHUM-Université de Montréal. Dr. Parker is an expert in neurodegenerative disease research using worms called C. elegans as models. He has several worms that mimic ALS and these are used to better understand how the disease is caused and to screen for potential treatments. Dr. Parker has been successful in attaining a number of grants through ALS Canada Research Program competitions. Most recently, he received a 2014 ALS Canada-Brain Canada Discovery Grant.
Credit: Amy Dumbleton
Dr. Neil Cashman is a neurologist, professor and researcher at University of British Columbia. He is a world leader in understanding the mechanisms by which SOD1 misfolding may propagate disease through cells and the body in both familial and sporadic ALS. He is also actively examining misfolding mechanisms of other ALS proteins and how they interact with SOD1. Dr. Cashman has been successful in attaining a number of grants through ALS Canada Research Program competitions. In 2015, he received a 2 year Bridge Grant.
(Credit: D'Arcy Hamilton, Momentum Media Productions)
Dr. Lorne Zinman, Director of the ALS Clinic at Sunnybrook Hospital in Toronto and Chair of the Canadian ALS Research Network (CALS), discusses his clinic, his research, CALS and the importance of the WALK for ALS.
(Credit: Amy Dumbleton)
Dr. Sanjay Kalra, a neuroimaging expert at University of Alberta, discusses his work on using novel techniques to understand brain degeneration in ALS and to determine how that might aid in diagnosis of the disease.
(Credit: Grant Wang)
Dr. Yana Yunusova, a speech-language pathologist at University of Toronto, discusses her clinical research focused on better understanding mechanisms of diagnosis and prognosis in individuals with bulbar ALS.
(Credit: John Temou, Culture Shock Productions, Inc)
Dr. Michael Strong, a pioneer in ALS research with more than 20 years' experience, comments on where your donated dollars go in research and the achievements of his lab at Western University
(Credit: Kristin Tate)
Please take a moment to watch clips of ALS researchers talk about nature of their work, what inspires them, what drives them to overcome obstacles, and what their hopes are for the future of ALS research.