Could decreasing the over-excitability of motor neurons be a new way to treat ALS?

Within the brain and spinal cord, neurons pass electrical signals to each other through specialized chemicals called neurotransmitters. When this signalling network functions properly, there is a good balance between chemicals that excite the neurons and chemicals that inhibit them. Both excitation and inhibition are necessary for the brain to function normally and send signals […]

What’s the story with CuATSM

This article was originally posted on the Motor Neurone Disease Association research blog on January 15, 2019. Thank you to the author Dr. Nicholas Cole, Head of Research, as well as the Motor Neuron Disease Association for giving ALS Canada permission to re-post this content.   There has recently been a flood of news stories […]

Do newly-discovered alternative proteins play a role in ALS?

Proteins are essential building blocks the body uses to make tissues such as muscles, cartilage, skin and blood. Conventional science assumes that a section of DNA known as a gene provides instructions for a single protein, or “encodes” a single protein. A molecule called messenger RNA carries those instructions for the production of one specific […]

ALS Research Matters

The realities of living with ALS – a challenging and terminal disease – led Carol Skinner and Eddy Lefrançois, two Canadians affected by ALS, to start a letter-writing campaign. The campaign encouraged fellow Canadians to contact their elected federal representative to ask for sustainable and direct ALS research funding. Over 2,300 Canadians joined Carol and […]

Cutting-edge technology allows University of Toronto researchers to tackle ALS in a new way.

Scientists have discovered variation within different areas of the brain and spinal cord of people living with ALS — some areas show greater degeneration while others are unaffected. With a $125,000 project grant from the ALS Canada Research Program in 2018, Dr. Janice Robertson and Dr. Paul McKeever, a postdoctoral fellow in her lab, will […]