Luckiest of the unlucky: keeping a positive mindset in the face of ALS

Norman MacIsaac says he’s the “luckiest of the unlucky.” His legs, arms and hands are failing him, his voice is weak, and his speech is slow and laboured, but he refuses to let ALS stifle his positivity. Norm has been on “voice rest” all day, so when we reach him by phone at his home […]

Can an animal model provide new insights into the formation of stress granules?

Alicia Dubinski may have inherited both her love for science and studying a neurodegenerative disease from her mother, a neuroscientist at the University of Toronto. When Dubinski was still a graduate student at the University of Waterloo, she met Dr. Christine Vande Velde at l’Université de Montréal in the Spring of 2019. She knew right […]

ALS Canada: Committed to the bright future of Canada’s ALS researchers

We are thrilled to share that the revamped ALS Canada Career Transition Award is accepting applications until Friday, February 21, 2020. This competition will help to support the next generation of scientists working toward a future without ALS. Originally launched in 2015, the competition ran for two years in partnership with Brain Canada (with the […]

Can new understandings about nuclear speckles lead to new treatment options for ALS?

In 2018, Dr. Ulises Rodriguez Corona was looking for a new research field where he could apply his knowledge and expertise in the biology of protein production in cells and the genetic instructions that control their behaviour. When he learned of an opportunity to perform high-tech research on protein-protein interactions in RNA metabolism in Dr. […]

Could newly discovered tags on TDP-43 protein explain its abnormal behaviour in ALS?

Overhearing one conversation was all it took to spark a new idea that became a funded ALS research project. Terry Suk, a PhD student working in the lab of Dr. Maxime Rousseaux at the University of Ottawa, heard Dr. Rousseaux and another student discuss a list of proteins in the brain that are modified by […]