Can probiotics play a protective role in ALS?

Probiotics are friendly, live bacteria that are good for the digestive system. You may be familiar with the digestive benefits of probiotics in foods like yogurt or kefir. Many scientists are investigating how changes in the composition of intestinal bacteria may play a role in a range of diseases including obesity, colorectal cancer, cardiovascular disease […]

Understanding if and how the body compensates for motor neuron loss in ALS

An electrical diagram of a building shows where all the electrical wires, fixtures and components are connected to an electrical system. When a circuit is faulty, it’s easy to identify the culprit because specific lights will not work. But the human nervous system is far more complicated. It is a living network of nerves that […]

Can a promising drug combination address one of the most defining biological characteristics of ALS?

All cells in our bodies make proteins, but sometimes they make mistakes, resulting in proteins that have the wrong shape. In a healthy body, protective mechanisms within the cells deal with the misshapen proteins so they don’t cause trouble, but when those mechanisms fail, the defective proteins can accumulate in clumps, making it difficult for […]

ALS Canada awards $3 million for 12 new research projects to help make amyotrophic lateral sclerosis (ALS) a treatable, not terminal disease

TORONTO, November 22, 2017 – Today, the ALS Society of Canada announced 12 exciting new research projects being funded in 2017 through the ALS Canada Research Program, which is supported by ALS Societies across Canada. The research being funded includes a multi-year study of a promising drug combination, three trainee grants that will help to […]

Strengthening Canada’s Excellence in ALS Clinical Trials

For a disease like ALS that has few treatment options and no cure, clinical trials are the best hope for the future. Participants in clinical trials play a critical role to help determine if a new treatment can slow, halt or reverse disease progression, or if a new intervention can improve the quality of life […]

Research to help people with ALS stay active and independent

Updated October 20, 2017 Staying active and independent for as long as possible is important for people living with ALS as the disease progresses. There are many ways in which to manage symptoms or receive care, but there often isn’t enough research performed to determine which approaches make the greatest difference. To help address these […]

Finding New Ways to Diagnose ALS Faster with Advanced Imaging

ALS is difficult to diagnose because no single test or procedure can firmly identify the disease. Current diagnostic tests for ALS focus on ruling out other diseases that share similar initial symptoms. For example, magnetic resonance imaging (MRI) is a test typically used to eliminate a diagnosis of cancer, multiple sclerosis or pressure on the […]

Maximizing the impact of donor dollars for ALS research

Finding new treatments that can change the course of ALS requires a robust research program, one that supports a large community of researchers exploring multiple avenues of inquiry. ALS Canada has been supporting world-class research across Canada for more than 30 years with a variety of grants and awards that are helping to learn more […]

Research Update, August 2017

ALS research is at a time of unprecedented advancement. New information on genes linked to ALS and the downstream effects of mutations in these genes has helped researchers to develop a so-called ‘roadmap’ of biological pathways that are important in ALS and to gain a better understanding of this complex disease. With new advancements being […]

The ALS Canada Research Program

Today was the deadline for applications from the research community for three different types of funding through the ALS Canada Research Program. Applications are evaluated by an international panel of scientific experts through a peer review process, regarded as the international benchmark of excellence in research funding. This approach enables us to maximize the impact […]

New Canadian investments in ALS research reflect growing knowledge about the disease and increasing likelihood of effective treatments being developed

The ALS Society of Canada (ALS Canada), in partnership with Brain Canada, today announced $4.5 million in funding for nine new ALS research projects. This means that since the Ice Bucket Challenge became a social media phenomenon in 2014, nearly $20 million has been invested in Canadian ALS research at a time when it has […]

Canada’s rising stars in ALS research receive more than $1 million from the ALS Canada Research Program and Brain Canada

The generosity of Canadians has helped three early-career researchers to make ALS the focus of their work in the country’s labs and academic institutions. The research funding, which totals more than $1 million, has been awarded through the ALS Canada Research Program and Brain Canada as a result of money raised through the Ice Bucket […]